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Systematic (IUPAC) name | |
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(R)-N-methyl-1-phenyl-propan-2-amine | |
Clinical data | |
Pregnancy cat. | ? |
Legal status | OTC |
Routes | Nasal Inhalation |
Pharmacokinetic data | |
Metabolism | Hepatic |
Excretion | Renal |
Identifiers | |
CAS number | 537-46-2 |
ATC code | ? |
PubChem | CID 36604 |
ChemSpider | 33634 |
UNII | 44RAL3456C |
KEGG | D02291 |
Chemical data | |
Formula | C10H15N |
Mol. mass | 149.2 |
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(what is this?) (verify) |
Levomethamphetamine (other names include l-methamphetamine, levodesoxyephedrine, l-desoxyephedrine, levmetamfetamine), is the levorotary (S-enantiomer) of methamphetamine. Levomethamphetamine is a sympathomimetic vasoconstrictor which is the active ingredient used in some over-the-counter nasal decongestants including the US formulation of Vicks Vapor Inhaler, but not the Canadian or Indian formulations, which contain just menthol and camphor.
Levomethamphetamine affects the sympathetic nervous system but has little activity in the central nervous system, so it is not thought to possess an addiction potential anywhere near that of racemic methamphetamine or dextromethamphetamine. Among its few physiological effects are the vasoconstriction that makes it useful for nasal decongestion.[1] The elimination half life of levomethamphetamine is between 13.3 and 15 hours.[2]
When used as a nasal decongestant, levomethamphetamine has potential side effects resembling those of other sympathomimetic drugs used for the same purpose; these effects include hypertension (elevated blood pressure), tachycardia (rapid heart rate), nausea, stomach cramps, dizziness, headache, and tremors.[citation needed]
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