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Definition and meaning of Clindamycine
Definitions
Clindamycine (n.)
1.(Cismef)Antibiotique dérivé de la lincomycine, actif contre les germes à Gram positif.
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Definition (more)
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Analogical dictionary
Clindamycine (n.)
[Cismef]
Lincomycine[Hyper.]
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Wikipedia
Clindamycine
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| Clindamycine | |
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| Général | |
| No CAS | |
| No EINECS | |
| Code ATC | D10 G01 J01 |
| DrugBank | |
| PubChem | |
| SMILES |
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| InChI |
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| Apparence | solide |
| Propriétés chimiques | |
| Formule brute | C18H33ClN2O5S [Isomères] |
| Masse molaire[1] | 424,983 ± 0,026 g·mol−1 C 50,87 %, H 7,83 %, Cl 8,34 %, N 6,59 %, O 18,82 %, S 7,55 %, |
| Propriétés physiques | |
| T° fusion | 255 °C |
| Solubilité | 30,6 mg·l-1 eau |
| Écotoxicologie | |
| DL50 | 2 618 mg·kg-1 rat s.c. |
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La clindamycine est un antibiotique. C'est un dérivé semi-synthétique de la lincomycine, proche des macrolides. Elle appartient à la famille des lincosamides.
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Contre indication
La solution topique de clindamycine est déconseillée:
- aux personnes allergiques aux médicaments contenant de la clindamycine ou de la lincomycine
- aux personnes possédant des antécédents de troubles stomacaux
- aux femmes enceintes et celles qui allaitent
Effet indésirables
L'effet secondaire le plus fréquent est la sécheresse et la desquamation de la peau, crampes, maux d'estomac, diarrhée, et nausées.
Spécialités contenant de la Clindamycine
- DALACINE
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Noms commerciaux :
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| Classe : anti-acnéique |
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| Autres informations : * inflammations des voies respiratoires et des poumons ainsi que dans le domaine ORL (par exemple, pharyngite, amygdalite, pneumonie, otite moyenne, sinusite, scarlatine, bronchite);
Sous classe: |
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Notes et références
- Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.
| Anti-acnéique |
|---|
| Adapalène | Acitrétine | Isotrétinoïne | Clindamycine | Peroxyde de benzoyle | Acide salicylique |
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