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Definition and meaning of Amikacine
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Analogical dictionary
Amikacine (n.)
[Cismef]
Kanamycine[Hyper.]
Wikipedia
Amikacine
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| Amikacine | |
|---|---|
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| Général | |
| No CAS | |
| No EINECS | |
| Code ATC | D06, J01, S01 |
| DrugBank | |
| PubChem | |
| SMILES |
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| InChI |
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| Apparence | solide |
| Propriétés chimiques | |
| Formule brute | C22H43N5O13 [Isomères] |
| Masse molaire[1] | 585,6025 ± 0,0255 g·mol−1 C 45,12 %, H 7,4 %, N 11,96 %, O 35,52 %, |
| Propriétés physiques | |
| T° fusion | 203 à 204 °C |
| Solubilité | 1,85.105 mg/L eau |
| Disulfate d'amikacine | |
 |
|
| Général | |
| No CAS | |
| No EINECS | |
| PubChem | |
| SMILES |
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| InChI |
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| Propriétés chimiques | |
| Formule brute | C22H47N5O21S2 [Isomères] |
| Masse molaire[2] | 781,759 ± 0,038 g·mol−1 C 33,8 %, H 6,06 %, N 8,96 %, O 42,98 %, S 8,2 %, |
| Écotoxicologie | |
| DL50 | >10 679 mg·kg-1 souris oral 181 mg·kg-1 souris i.v. 2 470 mg·kg-1 souris s.c. 2 930 mg·kg-1 souris i.p. |
| Classe thérapeutique | |
| antibiotique | |
| Considérations thérapeutiques | |
| Voie d’administration | IV, IM, SC |
| Précautions | Toxicité rénale et auditive |
| Sulfate d'amikacine | |
| Général | |
| No CAS | |
| PubChem | |
| SMILES |
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| InChI |
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| Propriétés chimiques | |
| Formule brute | C22H45N5O17S |
| Masse molaire[3] | 683,681 ± 0,032 g·mol−1 C 38,65 %, H 6,63 %, N 10,24 %, O 39,78 %, S 4,69 %, |
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 Amikacine et son sulfate |
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Noms commerciaux :
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| Classe : Antibiotique |
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| Autres informations : Sous classe : Aminoside |
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L'amikacine est un antibiotique aminoside proche de la gentamicine.
Notes et références
- Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.
- Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.
- Masse molaire calculée d’après Atomic weights of the elements 2007 sur www.chem.qmul.ac.uk.
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